Yohimbine — Fat Burning & Energy
Yohimbine — Fat Burning & Energy
What is yohimbine and how does it affect fat burning?
Yohimbine is an alkaloid derived from the bark of the West African yohimbe tree that acts as an alpha-2 adrenergic receptor antagonist. These receptors normally inhibit fat mobilization, especially in "stubborn" fat deposits (abdomen, hips, thighs). Yohimbine blocks these receptors, allowing adrenaline and noradrenaline to more effectively stimulate fat cells. The effective dose is 0.2 mg/kg body weight, but yohimbine must be taken on an empty stomach since insulin blocks its effect.
Frequently asked questions about yohimbine
Yohimbine is safe for most healthy individuals at recommended doses (0.2 mg/kg), but it has more side effects than most supplements. Possible effects include heart palpitations, anxiety, sweating, and elevated blood pressure. Yohimbine must not be used with hypertension, anxiety disorders, heart conditions, or MAO inhibitors.
Insulin released after eating activates alpha-2 receptors and negates yohimbine's fat-burning effect. Therefore, yohimbine should be taken in the morning on an empty stomach or at least 3-4 hours after the last meal. The most effective approach is combining yohimbine with fasted cardio training.
Yes, yohimbine is one of the few supplements specifically studied for stubborn fat deposits including abdominal fat. Studies show that yohimbine combined with endurance training reduced body fat percentage significantly more than training alone. The effect is greatest when combined with a calorie deficit and regular cardio.
Always start with the minimum dose (2.5 mg) and observe your body's reaction. Increase by 2.5 mg every 3-4 days until reaching your target dose (0.2 mg/kg). Never start with the full dose, as side effects like anxiety and heart palpitations can be unpleasant. Yohimbine requires very precise dosing.