Collagen: A Complete Overview
What is collagen?
Collagen is the most abundant protein in the human body, accounting for approximately 30% of total body protein. It is a structural protein found in skin, bones, tendons, ligaments, cartilage, and blood vessel walls.
Over 28 types of collagen have been identified. The types most commonly found in supplements are:
- Type I — the most prevalent, found in skin, bones, tendons, and connective tissue
- Type II — found primarily in cartilage
- Type III — found in skin, blood vessel walls, and internal organs
Raw material sources:
- Bovine collagen — derived from cowhide and bones, contains primarily type I and type III collagen
- Marine collagen — derived from fish skin and scales, contains primarily type I collagen
- Chicken collagen — derived from chicken sternum cartilage, contains primarily type II collagen
Hydrolysed vs native collagen:
- Hydrolysed collagen (collagen peptides) — collagen that has been enzymatically broken down into smaller peptides that dissolve easily in liquids
- Native (undenatured) collagen — collagen that retains its natural structure, typically used in smaller doses
Collagen supplements are widely available and popular across the Nordic countries, including Estonia.
How does it work?
The body naturally produces collagen using amino acids obtained from food. Collagen synthesis requires specific amino acids — primarily glycine, proline, and lysine — as well as co-factors such as vitamin C.
When collagen is consumed as a hydrolysed supplement, it is broken down in the digestive tract into peptides and amino acids, which are then absorbed from the small intestine into the bloodstream. Hydrolysed collagen (collagen peptides) has been broken down into smaller molecules that are water-soluble and more readily processed in the digestive system.
It is important to note that collagen has no EFSA (European Food Safety Authority) approved health claims. This means that no general health claims — such as improving skin elasticity, reducing joint discomfort, or strengthening hair — may be made about collagen supplements in the EU.
What does collagen contain?
Collagen has a unique amino acid composition that distinguishes it from most other proteins:
- Glycine — accounts for approximately 33% of collagen's amino acids, making it the most abundant amino acid in collagen
- Proline — accounts for approximately 10-12% of amino acids
- Hydroxyproline — a unique amino acid found almost exclusively in collagen, accounting for approximately 10% of amino acids
- Alanine — accounts for approximately 8-10% of amino acids
Collagen also contains smaller amounts of arginine, aspartic acid, glutamic acid, and other amino acids. For context, collagen is relatively low in essential amino acids such as tryptophan, which is why it is not considered a complete protein source.
Both marine and bovine collagen contain primarily glycine, proline, and hydroxyproline, although their precise amino acid profiles may vary slightly depending on the source.
Available forms
Powder
- The most common form, typically unflavoured or flavoured
- Dissolves in water, coffee, smoothies, and other beverages
- Allows flexible dosing
- Hydrolysed collagen dissolves better than gelatin
Capsules
- Convenient and portable
- Fixed dose per capsule
- Suitable for those who prefer a tasteless option
Liquid
- Ready-to-drink products and concentrates
- Often flavoured
- Convenient for immediate consumption
Flavoured vs unflavoured
- Unflavoured powder — suitable for adding to various drinks and foods without altering the taste profile
- Flavoured variants — available in various flavours (berry, lemon, chocolate), convenient to drink mixed with water on its own
How to take it
General usage guidelines:
- Always follow the recommended daily serving stated on the label — do not exceed it
- Collagen powder is typically mixed into water, coffee, tea, or smoothies
- Collagen dissolves in both hot and cold liquids, though it dissolves faster in hot liquids
- Timing is flexible — choose a convenient time that helps you remember to take it consistently
- Some people prefer taking it in the morning as part of their coffee or breakfast, others in the evening
- Capsules can be taken with water regardless of meal timing
Practical tips:
- Unflavoured collagen powder is nearly tasteless, making it compatible with many drinks and foods
- Start with the recommended dose and follow the label instructions
- Store in a cool, dry place
Who uses collagen supplements?
Collagen supplements are used by a range of people for various reasons:
- Athletes and physically active individuals — as an additional protein source with a specific amino acid profile
- Older adults — the body's natural collagen production decreases with age, making this a popular choice among this age group
- Beauty-conscious consumers — collagen has become a popular beauty supplement
- People seeking a specific amino acid profile — collagen's unique glycine- and proline-rich composition distinguishes it from other protein supplements
In Estonia and across Scandinavia, collagen supplements have become increasingly popular in recent years, available in health stores, pharmacies, and online shops.
Note: Before starting any supplement, it is advisable to consult a doctor, particularly if you have existing health conditions or are taking medications.
Frequently Asked Questions
What is the difference between hydrolysed collagen and gelatin?
Both are derived from collagen, but hydrolysed collagen (collagen peptides) has been broken down into smaller molecules than gelatin. Hydrolysed collagen dissolves in both hot and cold liquids and does not form a gel, whereas gelatin only dissolves in hot liquids and solidifies when cooled.
Does collagen have EFSA-approved health claims?
No, collagen does not have EFSA-approved health claims. This means that manufacturers in the EU may not claim that collagen improves skin, reduces joint discomfort, strengthens hair, or provides other health benefits.
Is collagen suitable for vegetarians or vegans?
Traditional collagen sources (bovine, marine, and chicken) are animal-derived and not suitable for vegans. There is currently no widely available plant-based collagen on the market, though some companies produce fermentation-based collagen.
When is the best time to take collagen?
There is no specific optimal time of day. Collagen can be taken at any time — morning, afternoon, or evening. Consistency is what matters. Choose a time that suits you and helps you remember your daily intake. Always follow the label instructions.
Can collagen be mixed into hot coffee?
Yes, hydrolysed collagen dissolves well in hot coffee, tea, and other hot beverages. The powder is typically tasteless and does not noticeably alter the flavour of the drink.
What is the difference between marine and bovine collagen?
Marine collagen is derived from fish skin and scales and contains primarily type I collagen. Bovine collagen is derived from cowhide and bones and contains primarily type I and type III collagen. Both have a similar amino acid composition, but the precise profile may vary slightly. The choice depends on personal preference and dietary restrictions.
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See also:
- Joint Health Supplements: Overview and Guide
- Collagen for Skin Elasticity After 40
- Collagen vs Whey Protein: Which to Choose?
- Hyaluronic Acid vs Collagen
Important information
Toidulisand ei asenda mitmekesist ja tasakaalustatud toitumist ega tervislikku eluviisi.
A food supplement is not a substitute for a varied and balanced diet and a healthy lifestyle.
Биологически активная добавка не является заменой разнообразного и сбалансированного питания и здорового образа жизни.



